The DME Studies will include patients with Diabetic Macular Edema (DME) and will be conducted at study sites across the USA. All study-related care will be provided by specialty physicians and a dedicated study team.

If you qualify for a study, you will visit a study clinic in your area.

The studies will be evaluating the efficacy of an investigational study drug for DME. Volunteers who qualify to take part in the study may receive compensation for time and travel expenses.

  • 1
    If you are aged 18 and above, have a diagnosis of Type 1 or Type 2 Diabetes Mellitus, have DME, and have never received previous therapy with antiangiogenic drugs.
  • 2
    All study-related care is provided at no cost. You do not need health insurance to participate.
  • 3
    Volunteers who take part in the study may be eligible to receive compensation for their time and travel.
  • 4
    Participants will receive all study-related care from a team of medical professionals at no cost. The study will require routine visits to a research center in your area.

Who can take part in the DME Studies?

You may be able to take part in the DME Studies if you:

  • 1
    Are 18 years of age or older.
  • 2
    Have been diagnosed with Type 1 or Type 2 Diabetes Mellitus.
  • 3
    Have Diabetic Macular Edema (DME).
  • 4
    Have never received previous therapy with antiangiogenic drugs.

All study-related care will be provided by a team of medical professionals.

Volunteers who take part in the study may be eligible to receive compensation for their time and travel.
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About Diabetic Macular Edema (DME)

Diabetic Macular Edema (DME) is a complication of diabetes caused by fluid accumulation in the macula, or central portion of the eye, that causes the macula to swell. This means that too much blood sugar has damaged the tiny blood vessels at the back, inner wall of the eye (the retina), or completely block the blood vessels. In order to develop DME, one must first have diabetic retinopathy. Diabetic retinopathy is a disease that damages the blood vessels in the retina, causing vision impairment. Left untreated, the blood vessels begin to build up pressure in the eye and leak fluid, causing DME.

DME is a serious condition that can cause vision problems, bulges (microaneurysms) that protrude from the eye and leak fluid into the retina, and in some cases, blindness.1

Common Symptoms of Diabetic Macular Edema include:

  • Slightly blurry vision
  • Wavy or double vision
  • Colors appearing washed out or faded
  • Vision loss
  • Eventual blindness if left untreated

It is important to get your eyes examined regularly for early detection to identify any eye health issues.

Current treatments for DME consist of maintaining the current vision of the patients, while preventing future vision loss. Some options are medical options that are injected or implanted into the eye, other treatments may be laser surgery to close leaking blood vessels. The goal of all treatments is to stop leakage in the macula.

Frequently Asked Questions

You can expect to attend study visits to a research center in your area.

All study-related care, trial-related medications, equipment, and supplies will be provided at no cost to you.

Health insurance is not required to participate.
Volunteers who take part in the study may receive reimbursement for their travel.

What is a clinical research study?

A Clinical research study (also called a clinical trial) is a medical study that helps to answer important questions about an investigational drug or device, such as: Does it work, or how effective is it compared to another drug/device?

All medications must be tested in clinical research studies before they can be approved by regulatory authorities for doctors to prescribe to patients. Without people taking part in these studies, we would have no new treatments. The volunteers who participate in clinical research studies play a major role in helping to advance medicine.

There is no cost to participate in the DME Studies. The investigational study drug, equipment, supplies, study-related tests, assessments, and visits will be provided at no cost to you. If you decide to take part:

  • You will receive study-related care throughout the study from a team of experienced doctors and nurses.
  • The study medication, study-related healthcare and supplies will be provided at no cost to you or your insurance company.

Volunteers who qualify to take part in the study may receive reimbursement for their travel. Please discuss this with the study team when they contact you.

Sign Up

What happens once I sign up? Once you sign up, we will match you to a study clinic in your area that is seeking participants or notify you when one becomes available. The study team will contact you to explain more about the study before you make your decision about participating. You will attend an in-person visit where the study team will help determine if you qualify and if the study is right for you.


If you think you might like to learn more about the DME Studies, please enter your information below so we can see if you qualify and can contact you about the study. And remember, participation is entirely voluntary. Even if you decide to take part in this study, you can change your mind about participating at any time.